Article
Thalassemia intermedia associated with the Hb Constant Spring EE Bart's disease in pregnancy: a molecular and hematological analysis.
Blood cells, molecules & diseases - 1 Jan 2000
Fucharoen Supan, Fucharoen Goonnapa, Sae-ung Nattaya, Sanchaisuriya Kanokwan
Abstract excerpt
We defined the molecular basis and analyzed hematological phenotype associated with an unusual form of thalassemia intermedia caused by interaction of the hemoglobin Constant Spring (Hb CS), homozygous Hb E and alpha degrees -thalassemia found in two unrelated pregnant Thai women. Both patients had moderate anemia and characteristic of thalassemia intermedia. Hb-HPLC analysis demonstrated in both cases, Hb E and...
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