Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Compound heterozygosity for alpha0-thalassemia (- -THAI) and Hb constant spring causes severe Hb H disease.

Hemoglobin - 1 May 2002

Viprakasit Vip, Tanphaichitr Voravarn S

Abstract excerpt

We report two unrelated cases of Hb H-Constant Spring (Hb H-CS) disease caused by a compound heterozygosity for alpha0-thalassemia (--THAI deletion) and Hb CS (alpha142, TAA-->CAA) in Thai patients. Hematological and clinical observations in the probands are more severe than those of deletional type of Hb H disease (- -/-alpha), owing to an early onset of anemia and recurrent episode of anemic crises. These cases...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Thalassemia
Share to Codon, Terminator
Share to Genetic Testing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hemoglobins, Abnormal

Share to Heterozygote

Share to Infant

Share to Sequence Deletion

Share to Thailand

Source

Identifiers

PMID: 12144058
DOI: 10.1081/hem-120005453

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Compound heterozygosity for alpha0-thalassemia (- -THAI) and Hb constant spring causes severe Hb H disease.PMID 12144058Read ↗

The First Thai Case of Nondeletional HbH Disease Caused by Compound Heterozygosity for α-Thalassemia-1 Chiang Rai (--CR) Type Deletion with Hb Constant Spring.Semantic proximity Read ↗

Molecular and clinical features of Hb H disease in northern Thailand.Semantic proximity Read ↗

Molecular and hematologic features of hemoglobin E heterozygotes with different forms of alpha-thalassemia in Thailand.Semantic proximity Read ↗

Hemoglobin Q-Thailand related disorders: origin, molecular, hematological and diagnostic aspects.Semantic proximity Read ↗

Acute haemolytic crisis in a Thai patient with homozygous haemoglobin Constant Spring (Hb CS/CS): a case report.Semantic proximity Read ↗

Molecular and hematological profiles of hemoglobin EE disease with different forms of alpha-thalassemia.Semantic proximity Read ↗

A large cohort of Hb H disease in northeast Thailand: A molecular revisited, diverse genetic interactions and identification of a novel mutation.Semantic proximity Read ↗

Thalassemia intermedia associated with the Hb Constant Spring EE Bart's disease in pregnancy: a molecular and hematological analysis.Semantic proximity Read ↗

Hb H disease with various β hemoglobinopathies: molecular, hematological and diagnostic aspects.Semantic proximity Read ↗

Complex Interaction of Hb Q-Thailand with α0- and β0-Thalassemia in a Chinese Family.Semantic proximity Read ↗

Molecular spectrum of Hb H disease and characterization of rare deletional α-thalassemia found in ThailandSemantic proximity Read ↗

Association of Hb Q-Thailand with homozygous Hb E and heterozygous Hb Constant Spring in pregnancy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.