Article
Phenotype and Genotype in a Cohort of 312 Adult Patients with Nontransfusion-Dependent Thalassemia in Northeast Thailand.
Acta haematologica - 1 Jan 2016
Prayalaw Patcharawadee, Teawtrakul Nattiya, Jetsrisuparb Arunee, Pongudom Saranya, Fucharoen Goonnapa, Fucharoen Supan
Abstract excerpt
Patients with nontransfusion-dependent thalassemia (NTDT) do not require regular blood transfusion for survival but may encounter several complications that contribute to morbidity and mortality. We report the molecular heterogeneity and hematological features of NTDT in 312 adult patients in northeast Thailand. Hemoglobin (Hb) and DNA analyses identified 177 subjects with Hb E-β-thalassemia, 1 with homozygous...
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