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Article

Activation of Signaling Pathways and Stress-Response Genes in an Experimental Model of Retinal Detachment

24 Mar 2006

Abstract excerpt

PURPOSE: Despite the high metabolic demands of the neural retina, its detachment from the retinal pigment epithelium does not lead to immediate death for most of the cells. This study was undertaken to test the hypothesis that intrinsic protective mechanisms are activated in the neural retina during early stages of retinal detachment. METHODS: Retinal detachments were created in Brown Norway rats by injection of...

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PMID: 16565410
DOI: 10.1167/iovs.05-1209

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