Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trypanosoma cruzi: infectivity modulation of a clone after passages through different hosts.

Experimental parasitology - 1 Oct 2006

Pérez Brandán Cecilia, Padilla Angel Marcelo, Diosque Patricio, Basombrío Miguel Angel

Abstract excerpt

Although Trypanosoma cruzi virulence can be modified through passages in vivo or long-term in vitro culture, the mechanisms involved are poorly understood. Here we report modifications in the infectivity of a T. cruzi clone after passages in different hosts without detectable changes in parasite genetic patterns. A clone was obtained from a T. cruzi IIe isolate and showed to be less virulent than the original...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chagas Disease
Share to Cloning, Organism
Share to Electrophoresis, Starch Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guinea Pigs

Share to Host-Parasite Interactions

Share to Parasitemia

Share to Serial Passage

Share to Trypanosoma cruzi

Source

Identifiers

PMID: 16564526
DOI: 10.1016/j.exppara.2006.02.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trypanosoma cruzi: infectivity modulation of a clone after passages through different hosts.PMID 16564526Read ↗

<i>Trypanosoma cruzi</i> isolates naturally adapted to congenital transmission display a unique strategy of transplacental passageSemantic proximity Read ↗

Effects of long-term<i>in vitro</i>cultivation on the virulence of cloned lines of<i>Leishmania major</i>promastigotesSemantic proximity Read ↗

Genomic variation in Trypanosoma cruzi clonal cultures.Semantic proximity Read ↗

Impairment of infectivity and immunoprotective effect of a LYT1 null mutant of Trypanosoma cruzi.Semantic proximity Read ↗

Genotype and virulence correlation within Mexican stocks of Trypanosoma cruzi isolated from patients.Semantic proximity Read ↗

Trypanosoma cruzi: long-term sub-cultures in two different culture media do not confirm the existence of highly versatile multilocus genotypes.Semantic proximity Read ↗

Host-passage-induced phenotypic changes in crimean-congo haemorrhagic fever virus.Semantic proximity Read ↗

Change in phenotype of tick-borne encephalitis virus following passage in Ixodes ricinus ticks and associated amino acid substitution in the envelope protein.Semantic proximity Read ↗

Biological and molecular characterization of a raccoon isolate of Trypanosoma cruzi from South Carolina.Semantic proximity Read ↗

High- and low-infectivity phenotypes of clonal populations of in vitro-cultured Borrelia burgdorferi.Semantic proximity Read ↗

Host-Parasite Interactions in Chagas Disease: Genetically Unidentical Isolates of a Single Trypanosoma cruzi Strain Identified In Vitro via LSSP-PCR.Semantic proximity Read ↗

Differential accumulation of genetic and phenotypic changes in Venezuelan equine encephalitis virus and Japanese encephalitis virus following passage in vitro and in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.