Article
Host-Parasite Interactions in Chagas Disease: Genetically Unidentical Isolates of a Single Trypanosoma cruzi Strain Identified In Vitro via LSSP-PCR.
PloS one - 1 Jan 2015
Nogueira-Paiva Nívia Carolina, Vieira Paula Melo de Abreu, Oliveri Larissa Maris Rezende, Fonseca Kátia da Silva, Pound-Lana Gwenaelle, de Oliveira Maykon Tavares, de Lana Marta, Veloso Vanja Maria, Reis Alexandre Barbosa, Tafuri Washington Luiz, Carneiro Cláudia Martins
Abstract excerpt
The present study aims at establishing whether the diversity in pathogenesis within a genetically diverse host population infected with a single polyclonal strain of Trypanosoma cruzi is due to selection of specific subpopulations within the strain. For this purpose we infected Swiss mice, a genetically diverse population, with the polyclonal strain of Trypanosoma cruzi Berenice-78 and characterized via LSSP-PCR...
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