Article
Host-passage-induced phenotypic changes in crimean-congo haemorrhagic fever virus.
Research in virology - 1 Jan 2000
Gonzalez J P, Wilson M L, Cornet J P, Camicas J L
Abstract excerpt
Changes in virulence of Crimean-Congo haemorrhagic fever (CCHF) virus toward intracerebrally inoculated suckling mice (SM) were studied in relation to different host-passage histories. Two CCHF virus strains, one isolated from a human and the other from a tick, were passaged through various vertebrate and tick hosts and then reisolated and tested for their virulence toward SM. In various experiments, SM were...
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