Article
Genomic variation in Trypanosoma cruzi clonal cultures.
Parasitology research - 1 Jan 1996
Alves A M, de Almeida D F, von Krüger W M
Abstract excerpt
Spontaneous changes in restriction DNA profiles and pulsed-field gel electrophoresis (PFGE) patterns, along with a concomitant loss of infectivity, were observed in infective clones of Trypanosoma cruzi strain Y either following a number of passages during the exponential growth phase of after subcloning in liver infusion tryptone (LIT) medium using as the probe a genomic fragment of the parasite (pMYP16),...
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