High- and low-infectivity phenotypes of clonal populations of in vitro-cultured Borrelia burgdorferi.

doi:10.1128/iai.63.6.2206-2212.1995

Back to search

Article

High- and low-infectivity phenotypes of clonal populations of in vitro-cultured Borrelia burgdorferi.

Infection and immunity - 1 Jun 1995

Norris S J, Howell J K, Garza S A, Ferdows M S, Barbour A G

Abstract excerpt

Borrelias that cause Lyme disease lose the ability to infect and cause disease in laboratory animals following 10 to 16 passages of in vitro culture. In this study, clonal populations of the Sh-2-82 (Sh2) and B31 strains of Borrelia burgdorferi were isolated by subsurface plating on BSK-II agar p...

Topics

Animals
Bacterial Proteins
Borrelia burgdorferi Group
Female
Mice
Mice, Inbred C3H
Mice, SCID
Phenotype
Plasmids
Virulence

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.