Article

Modification and validation of a GAD-GFP mouse line without accelerated aging-related hearing loss

2025-04-03

Abstract excerpt

<h4>ABSTRACT</h4> GABAergic neurons in the inferior colliculus (IC) play a crucial role in auditory processing by extracting specific features of sounds (Ono et al., 2005). The Gad67-GFP mouse model developed by Tamamaki et al. in 2003 on a Swiss background facilitates studying these neurons by using a green fluorescent protein that is expressed endogenously via the GAD67 promoter. Unfortunately, this mouse suffe...

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Literature Corpus work: 4ea7d0bc-eb7f-504f-be9d-241cb379f0e8
DOI: 10.1101/2025.03.29.646110

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