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Article

Postnatal development of the organ of Corti in dominant-negative Gjb2 transgenic mice.

Neuroscience - 28 Oct 2008

Inoshita A, Iizuka T, Okamura H-O, Minekawa A, Kojima K, Furukawa M, Kusunoki T, Ikeda K

Abstract excerpt

Hereditary hearing loss is one of the most prevalent inherited human birth defects, affecting one in 2000. A strikingly high proportion (50%) of congenital bilateral nonsyndromic sensorineural deafness cases have been linked to mutations in the GJB2 coding for the connexin26. It has been hypothesized that gap junctions in the cochlea, especially connexin26, provide an intercellular passage by which K(+) are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18793701
DOI: 10.1016/j.neuroscience.2008.08.027

Genes

GJB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Postnatal development of the organ of Corti in dominant-negative Gjb2 transgenic mice.PMID 18793701Read ↗

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