Article
A novel Val734Ile variant in the ABCC9 gene associated with myocardial infarction.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2006
Minoretti Piercarlo, Falcone Colomba, Aldeghi Alessia, Olivieri Valentina, Mori Francesca, Emanuele Enzo, Calcagnino Margherita, Geroldi Diego
Abstract excerpt
BACKGROUND: Alterations in coronary vasomotor tone are deemed to play an important role in myocardial infarction (MI), and the ATP-binding cassette transporter C9-ABCC9-may be involved in the regulation of coronary artery vasomotility. We sought to determine whether genetic variations in the coding sequence of ABCC9 gene could be associated with precocious MI (myocardial infarction before the age of 60 years) in...
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