Article
Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage renal disease.
American journal of hypertension - 1 Dec 2005
Spoto Belinda, Benedetto Francesco A, Testa Alessandra, Tripepi Giovanni, Mallamaci Francesca, Maas Renke, Boeger Rainer H, Zoccali Carmine, Parlongo Rosa Maria, Pisano Anna
Abstract excerpt
BACKGROUND: We investigated whether the eNOS G/T polymorphism (Glu298Asp variant) is linked to the severity of carotid atherosclerosis and whether it is independent of asymmetric dimethylarginine (ADMA) in determining vascular damage in patients with end-stage renal disease (ESRD). METHODS: The eNOS polymorphism, ADMA, carotid intima-media thickness (IMT), and carotid artery (CCA) wall-to-lumen ratio (an...
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