Article
AFR1 promotes polarized apical morphogenesis in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Feb 1995
Konopka J B, DeMattei C, Davis C
Abstract excerpt
The G protein-coupled alpha-factor receptor promotes polarized growth toward a mating partner. alpha-Factor induces the expression of AFR1, which acts together with the receptor C terminus to promote normal morphogenesis. The function of AFR1 was investigated by engineering cells to constitutively express AFR1 without alpha-factor. Constitutive AFR1 expression caused cells to form elongated buds that demonstrate...
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