Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of hemagglutinin/protease and motility to the pathogenesis of El Tor biotype cholera.

Infection and immunity - 1 Apr 2006

Silva Anisia J, Leitch Gordon J, Camilli Andrew, Benitez Jorge A

Abstract excerpt

Vibrio cholerae is a highly motile organism that secretes a Zn-dependent metalloprotease, hemagglutinin/protease (HapA). HapA has been shown to have mucinase activity and contribute to the reactogenicity of live vaccine candidates, but its role in cholera pathogenesis is not yet clear. The contribution of motility to pathogenesis is not fully understood, since conflicting results have been obtained with different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Suckling
Share to Cholera
Share to Flagella

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Metalloendopeptidases

Share to Movement

Share to Polysaccharide-Lyases

Share to Vibrio cholerae

Source

Open in PubMed Open full text

Identifiers

PMID: 16552036
DOI: 10.1128/IAI.74.4.2072-2079.2006
PMCID: PMC1418906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of hemagglutinin/protease and motility to the pathogenesis of El Tor biotype cholera.PMID 16552036Read ↗

Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression.Semantic proximity Read ↗

Flagellum-independent surface migration of Vibrio cholerae and Escherichia coli.Semantic proximity Read ↗

Analysis of the Vibrio pathogenicity island-encoded Mop protein suggests a pleiotropic role in the virulence of epidemic Vibrio cholerae.Semantic proximity Read ↗

Vibrio cholerae hemagglutinin/protease, colonial variation, virulence, and detachment.Semantic proximity Read ↗

The role of toxin-coregulated pili in the pathogenesis of Vibrio cholerae O1 El Tor.Semantic proximity Read ↗

Pathogenic and vaccine significance of toxin-coregulated pili of Vibrio cholerae E1 Tor.Semantic proximity Read ↗

Identification of the Vibrio cholerae type 4 prepilin peptidase required for cholera toxin secretion and pilus formation.Semantic proximity Read ↗

Genetic characterization of mannose-sensitive hemagglutinin (MSHA)-negative mutants of Vibrio cholerae derived by Tn5 mutagenesis.Semantic proximity Read ↗

Motility mutants of Vibrio cholerae O1 have reduced adherence in vitro to human small intestinal epithelial cells as demonstrated by ELISA.Semantic proximity Read ↗

Mutations in the MotA protein of Escherichia coli reveal domains critical for proton conduction.Semantic proximity Read ↗

Physical linkage of the Vibrio cholerae mannose-sensitive hemagglutinin secretory and structural subunit gene loci: identification of the mshG coding sequence.Semantic proximity Read ↗

Expression of Cholera Toxin (CT) and the Toxin Co-Regulated Pilus (TCP) by Variants of ToxT in Vibrio cholerae Strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.