Article
Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression.
Infection and immunity - 1 Jun 1996
Gardel C L, Mekalanos J J
Abstract excerpt
Motility is thought to contribute to the virulence of Vibrio cholerae, but the role it plays in pathogenesis is not completely understood. To investigate the influence of motility on virulence gene expression and intestinal colonization, we have isolated mutants with altered swarming abilities in soft agar medium. Both spontaneous hyperswarmer (exhibiting faster swarm rates) and spontaneous or transposon-induced...
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