Article
Pathogenic and vaccine significance of toxin-coregulated pili of Vibrio cholerae E1 Tor.
Journal of biotechnology - 20 Aug 1999
Attridge S R, Voss E, Manning P A
Abstract excerpt
Vibrio cholerae O1 strains are classified into one of two biotypes, classical and E1 Tor, the latter being primarily responsible for cholera cases worldwide since 1961. Recent studies in our laboratory have focused upon the pathogenic and vaccine significance of the toxin-coregulated pili (TCP) produced by strains of E1 Tor biotype. Mutants in which the tcpA gene (encoding the pilin subunit protein) has been...
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