Article
Plasma thrombopoietin compared with immunoglobulin heavy-chain mutation status as a predictor of survival in chronic lymphocytic leukemia.
Blood - 1 Aug 2006
Koller Charles, Bekele B Nebiyou, Zhou Xian, Park Charles, Estrov Zeev, O'Brien Susan, Keating Michael, Jilani Iman, Giles Francis J, Kantarjian Hagop M, Albitar Maher
Abstract excerpt
We investigated the association of plasma thrombopoietin (TPO) and overall survival in 127 patients with previously treated and previously untreated chronic lymphocytic leukemia (CLL). Higher levels of TPO were associated with advanced Rai stage (P < .001), higher levels of beta(2)-microglobulin (beta2-M) (P < .001), and the absence of mutation in the immunoglobulin heavy chain variable region (IgV(H)) (P <...
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