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Article

Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia.

Blood - 15 Jan 2008

Gattei Valter, Bulian Pietro, Del Principe Maria Ilaria, Zucchetto Antonella, Maurillo Luca, Buccisano Francesco, Bomben Riccardo, Dal-Bo Michele, Luciano Fabrizio, Rossi Francesca M, Degan Massimo, Amadori Sergio, Del Poeta Giovanni

Abstract excerpt

CD49d/alpha4-integrin is variably expressed in chronic lymphocytic leukemia (CLL). We evaluated its relevance as independent prognosticator for overall survival and time to treatment (TTT) in a series of 303 (232 for TTT) CLLs, in comparison with other biologic or clinical prognosticators (CD38, ZAP-70, immunoglobulin variable heavy chain (IGHV) gene status, cytogenetic abnormalities, soluble CD23,...

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Share to Aged, 80 and over
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Gene Expression Regulation, Leukemic

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Source

Identifiers

PMID: 17959854
DOI: 10.1182/blood-2007-05-092486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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