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Article

TP53 mutation and survival in chronic lymphocytic leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Oct 2010

Zenz Thorsten, Eichhorst Barbara, Busch Raymonde, Denzel Tina, Häbe Sonja, Winkler Dirk, Bühler Andreas, Edelmann Jennifer, Bergmann Manuela, Hopfinger Georg, Hensel Manfred, Hallek Michael, Döhner Hartmut, Stilgenbauer Stephan

Abstract excerpt

PURPOSE: The precise prognostic impact of TP53 mutation and its incorporation into treatment algorithms in chronic lymphocytic leukemia (CLL) is unclear. We set out to define the impact of TP53 mutations in CLL. PATIENTS AND METHODS: We assessed TP53 mutations by denaturing high-performance liquid chromatography (exons 2 to 11) in a randomized prospective trial (n = 375) with a follow-up of 52.8 months (German...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20697090
DOI: 10.1200/JCO.2009.27.8762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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