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Article

The Biology of Chronic Lymphocytic Leukemia: Diagnostic and Prognostic Implications.

Cancer journal (Sudbury, Mass.) - 1 Jan 2000

Moia Riccardo, Patriarca Andrea, Schipani Mattia, Gaidano Gianluca

Abstract excerpt

ABSTRACT: The high degree of clinical heterogeneity of chronic lymphocytic leukemia (CLL) is influenced by the disease molecular complexity. Genetic studies have allowed to better understand CLL biology and to identify molecular biomarkers of clinical relevance. TP53 disruption represents the strongest prognosticator of chemorefractoriness and indicates the use of Bruton tyrosine kinase inhibitors (BTKis) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34398553
DOI: 10.1097/PPO.0000000000000534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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