Article
Protein-membrane interaction and fatty acid transfer from intestinal fatty acid-binding protein to membranes. Support for a multistep process.
The Journal of biological chemistry - 19 May 2006
Falomir-Lockhart Lisandro J, Laborde Lisandro, Kahn Peter C, Storch Judith, Córsico Betina
Abstract excerpt
Fatty acid transfer from intestinal fatty acid-binding protein (IFABP) to phospholipid membranes occurs during protein-membrane collisions. Electrostatic interactions involving the alpha-helical "portal" region of the protein have been shown to be of great importance. In the present study, the role of specific lysine residues in the alpha-helical region of IFABP was directly examined. A series of point mutants in...
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