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Article

3' end processing of the prothrombin mRNA in thrombophilia.

Acta haematologica - 1 Jan 2006

Danckwardt Sven, Hartmann Kathrin, Gehring Niels H, Hentze Matthias W, Kulozik Andreas E

Abstract excerpt

Clinical and genetic studies have led to the discovery of specific genotypes that predispose to thromboembolism in adults and children. The exploration of the underlying pathologies has revealed a broad variety of affected molecular mechanisms. Most recently, the functional analysis of the prothrombin (F2) 20210*A variant revealed increased efficiency of 3' end processing as a novel genetic mechanism predisposing...

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Identifiers

PMID: 16549895
DOI: 10.1159/000090934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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