Article
Triglyceride-rich HDL3 from patients with familial hypercholesterolemia are less able to inhibit cytokine release or to promote cholesterol efflux.
The Journal of nutrition - 1 Apr 2006
Ottestad Inger O, Halvorsen Bente, Balstad Trude R, Otterdal Kari, Borge Grethe I, Brosstad Frank, Myhre Anne M, Ose Leiv, Nenseter Marit S, Holven Kirsten B
Abstract excerpt
Familial hypercholesterolemia (FH) is associated with heterogeneity of the onset and severity of coronary heart disease (CHD). In this study, we investigated different low-grade proinflammatory markers and the atheroprotective function of the HDL3 subfraction in FH-patients (n = 13) with identical LDL-receptor mutations and in age- and sex-matched healthy controls (n = 11). Compared with healthy controls,...
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