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Article

Immature NK cells suppress dendritic cell functions during the development of leukemia in a mouse model.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2006

Ebata Kazumi, Shimizu Yukihiro, Nakayama Yasuhiro, Minemura Masami, Murakami Jun, Kato Tsutomu, Yasumura Satoshi, Takahara Terumi, Sugiyama Toshiro, Saito Shigeru

Abstract excerpt

To analyze the mechanisms by which cancer cells escape from hosts' immune surveillance, we investigated the changes in immune status during the progression of leukemia induced by injecting mice with WEHI-3B cells. In the bone marrow (BM) of leukemic mice, only DX5(+)CD3(-) cells were continuously increased, despite the progression of leukemia. In addition, DX5(+)CD3(-) cells were rapidly increased in peripheral...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16547247
DOI: 10.4049/jimmunol.176.7.4113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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