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Article

Cdc42-driven podosome formation in endothelial cells.

European journal of cell biology - 1 Apr 2006

Moreau Violaine, Tatin Florence, Varon Christine, Anies Guerric, Savona-Baron Catherine, Génot Elisabeth

Abstract excerpt

Ectopic expression of a constitutive active mutant of the GTPase Cdc42 (V12Cdc42) in vascular endothelial cells triggers the dissolution of stress fibres and focal adhesion contacts and causes the repolymerisation of actin into dots. Each punctate structure consists of an F-actin core surrounded by a vinculin ring, consistent with the definition of podosomes. We now report further analysis of these complexes and...

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Source

Identifiers

PMID: 16546575
DOI: 10.1016/j.ejcb.2005.09.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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