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Article

Subconfluent endothelial cells form podosomes downstream of cytokine and RhoGTPase signaling.

Experimental cell research - 15 Jul 2005

Osiak Anna-Eleonor, Zenner Gerhardt, Linder Stefan

Abstract excerpt

Adhesion, migration and invasion of endothelial cells are prerequisites for the formation of blood vessels and have to be controlled on a subcellular level. We report that subconfluent human umbilical vein endothelial cells (HUVEC) are able to constitutively form podosomal adhesions that are sites of matrix metalloprotease concentration and matrix degradation. Importantly, incubation of serum-starved cells with...

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Identifiers

PMID: 15894313
DOI: 10.1016/j.yexcr.2005.03.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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