Article
Genomic instability and tissue expression of angiogenic growth factors in sporadic colorectal cancer.
Surgery - 1 Mar 2006
Inoue Yasuhiro, Miki Chikao, Watanabe Hideki, Ojima Eiki, Kusunoki Masato
Abstract excerpt
BACKGROUND: Chromosomal instability evidenced by a loss of heterozygosity (LOH) is implicated as a predictor of poor survival in patients with colorectal cancer, whereas microsatellite instability (MSI) is associated with improved survival rates. We investigated the relationship between tumor expression of angiogenic growth factors and genomic alterations in colorectal cancer. METHODS: Two genotypes, LOH and MSI,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
