Article
Competitive allele-specific short oligonucleotide hybridization (CASSOH) with enzyme-linked immunosorbent assay (ELISA) for the detection of pharmacogenetic single nucleotide polymorphisms (SNPs).
Journal of biochemical and biophysical methods - 30 Jun 2006
Hiratsuka Masahiro, Ebisawa Aiko, Sakuyama Kanako, Matsubara Yoichi, Kure Shigeo, Soya Yoshihiro, Konno Yumiko, Sasaki Takamitsu, Kishiba Akiko, Mizugaki Michinao
Abstract excerpt
Individualization of drug therapy through genetic testing would maximize the effectiveness of medication and minimize its risks. Recent progress in genetic testing technologies has been remarkable, and they have been applied for the analysis of genetic polymorphisms that regulate drug responses. Clinical application of genetic information to individual health care requires simple and rapid identification of...
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