Article
Identification of a novel VNTR polymorphism in C6orf37 and its association with colorectal cancer risk in Chinese population.
Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2006
Cui Jing, Wang Wei, Lai Mao-De, Xu En-Ping, Lv Bing-Jian, Lin Jie, Ruan Wen-Jing, Ma Yu, Yao Chan
Abstract excerpt
BACKGROUND: C6orf37 was a gene up-regulated in colorectal adenoma in our previous study. A variable region of C6orf37 sequence was found when we blasted its full sequence with NCBI nucleotide database. METHODS: RT-PCR and sequencing were conducted to identify the variable region of C6orf37 as VNTR. DHPLC was applied to detect the VNTR genotypes in 122 colorectal carcinoma patients and 166 healthy controls....
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