Article
Common genetic variation in ETV6 is associated with colorectal cancer susceptibility.
Nature communications - 5 May 2016
Wang Meilin, Gu Dongying, Du Mulong, Xu Zhi, Zhang Suzhan, Zhu Lingjun, Lu Jiachun, Zhang Rui, Xing Jinliang, Miao Xiaoping, Chu Haiyan, Hu Zhibin, Yang Lei, Tang Cuiju, Pan Lei, Du Haina, Zhao Jian, Du Jiangbo, Tong Na, Sun Jielin, Shen Hongbing, Xu Jianfeng, Zhang Zhengdong, Chen Jinfei
Abstract excerpt
Genome-wide association studies (GWASs) have identified multiple susceptibility loci for colorectal cancer, but much of heritability remains unexplained. To identify additional susceptibility loci for colorectal cancer, here we perform a GWAS in 1,023 cases and 1,306 controls and replicate the findings in seven independent samples from China, comprising 5,317 cases and 6,887 controls. We find a variant at 12p13.2...
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