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Article

Fibrocyte localisation to the ASM bundle in asthma: bidirectional effects on cell phenotype and behaviour

1 Jan 2020

Abstract excerpt

Abstract Objectives Airway hyper‐responsiveness and persistent airflow obstruction contribute to asthma pathogenesis and symptoms, due in part to airway smooth muscle (ASM) hypercontractility and increased ASM mass. Fibrocytes have been shown to localise to the ASM in asthma however it is not known whether fibrocytes localise to the ASM in nonasthmatic eosinophilic bronchitis (NAEB) and chronic obstructive...

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PMID: 33209301
DOI: 10.1002/cti2.1205

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