Article
Postaxial polydactyly in forelimbs of CRABP-II mutant mice.
Development (Cambridge, England) - 1 Mar 1995
Fawcett D, Pasceri P, Fraser R, Colbert M, Rossant J, Giguère V
Abstract excerpt
The cytoplasmic retinoic acid (RA)-binding protein CRABP-II is expressed widely throughout early morphogenesis in mouse embryo, but its expression becomes more restricted as organogenesis progresses. CRABP-II expression remains strong in the developing limb bud suggesting a role for this protein in limb patterning. Here, we show that the CRABP-II promoter can direct expression of a lacZ transgene in a specific...
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