Article
Postaxial polydactyly in forelimbs of CRABP-II mutant mice.
Development (Cambridge, England) - 1 Mar 1995
Fawcett D, Pasceri P, Fraser R, Colbert M, Rossant J, Giguère V
Abstract excerpt
The cytoplasmic retinoic acid (RA)-binding protein CRABP-II is expressed widely throughout early morphogenesis in mouse embryo, but its expression becomes more restricted as organogenesis progresses. CRABP-II expression remains strong in the developing limb bud suggesting a role for this protein...
Topics
- Animals
- Forelimb
- Gene Expression
- Immunohistochemistry
- Mice
- Mice, Transgenic
- Morphogenesis
- Phenotype
- Polydactyly
- Promoter Regions, Genetic
- Receptors, Retinoic Acid
- Signal Transduction
- Tretinoin