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Article

Deciphering cellular states of innate tumor drug responses

15 Mar 2006

Abstract excerpt

BACKGROUND: The molecular mechanisms underlying innate tumor drug resistance, a major obstacle to successful cancer therapy, remain poorly understood. In colorectal cancer (CRC), molecular studies have focused on drug-selected tumor cell lines or individual candidate genes using samples derived from patients already treated with drugs, so that very little data are available prior to drug treatment. RESULTS:...

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PMID: 16542501
DOI: 10.1186/gb-2006-7-3-r19

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