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Article

MTHFR C677 T gene polymorphism in lymphoproliferative diseases.

Journal of clinical laboratory analysis - 1 Jan 2006

Deligezer Ugur, Akisik Ebru E, Yaman Fulya, Erten Nilgün, Dalay Nejat

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR), a key enzyme in folate metabolism, has been implicated in cancer risk. In the present study we used a melting curve analysis to investigate the association of the common MTHFR C677 T polymorphism with lymphoproliferative diseases. Patients (n=117) were compared with age- and sex-matched control subjects (n=154). Our results indicate that the 677 T variant occurred less...

Topics

Adult
Aged
Alleles
DNA Mutational Analysis
Female
Genotype
Humans
Lymphoproliferative Disorders
Male
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 16538645
DOI: 10.1002/jcla.20103
PMCID: PMC6807388

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16538645-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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MTHFR C677 T gene polymorphism in lymphoproliferative diseases.PMID 16538645Read ↗

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