Article
MTHFR C677 T gene polymorphism in lymphoproliferative diseases.
Journal of clinical laboratory analysis - 1 Jan 2006
Deligezer Ugur, Akisik Ebru E, Yaman Fulya, Erten Nilgün, Dalay Nejat
Abstract excerpt
Methylenetetrahydrofolate reductase (MTHFR), a key enzyme in folate metabolism, has been implicated in cancer risk. In the present study we used a melting curve analysis to investigate the association of the common MTHFR C677 T polymorphism with lymphoproliferative diseases. Patients (n=117) were compared with age- and sex-matched control subjects (n=154). Our results indicate that the 677 T variant occurred less...
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