Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of BAF57 mutations in human breast cancer cell lines.

Breast cancer research and treatment - 1 Jul 2006

Kiskinis Evangelos, García-Pedrero Juana M, Villaronga M Angeles, Parker Malcolm G, Belandia Borja

Abstract excerpt

Accumulating genetic and biochemical evidences support a role for the SWI/SNF chromatin-remodeling complex in cancer development and multiple core subunits of these complexes have been found to function as tumor suppressor genes. The core SWI/SNF subunit BAF57 mediates direct interactions with estrogen and androgen receptors (ER and AR) regulating their transcriptional activity. BAF57 gene maps to chromosome band...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Cell Line, Tumor

Share to Chromosomal Proteins, Non-Histone

Share to DNA-Binding Proteins

Share to Estrogen Receptor alpha

Share to Molecular Sequence Data

Source

Identifiers

PMID: 16538531
DOI: 10.1007/s10549-005-9149-9

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of BAF57 mutations in human breast cancer cell lines.PMID 16538531Read ↗

Identification and characterization of novel potentially oncogenic mutations in the human BAF57 gene in a breast cancer patient.Semantic proximity Read ↗

Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignanciesSemantic proximity Read ↗

The developmental and pathogenic roles of BAF57, a special subunit of the BAF chromatin‐remodeling complexSemantic proximity Read ↗

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.Semantic proximity Read ↗

Research progress of SWI/SNF complex in breast cancer.Semantic proximity Read ↗

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomicsSemantic proximity Read ↗

Loss of function of SWI/SNF chromatin remodeling genes leads to genome instability of human lung cancerSemantic proximity Read ↗

The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene.Semantic proximity Read ↗

Frequent mutations in the amino-terminal domain of BCL7A impair its tumor suppressor role in DLBCL.Semantic proximity Read ↗

N‐terminally truncated BAF57 isoforms contribute to the diversity of SWI/SNF complexes in neuronsSemantic proximity Read ↗

The chromatin remodeler SMARCD3 regulates cell cycle progression and its expression predicts survival outcome in ER+ breast cancerSemantic proximity Read ↗

Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.