Article
Identification and characterization of novel potentially oncogenic mutations in the human BAF57 gene in a breast cancer patient.
Breast cancer research and treatment - 1 Aug 2011
Villaronga M Angeles, López-Mateo Irene, Markert Linn, Espinosa Enrique, Fresno Vara Juan Angel, Belandia Borja
Abstract excerpt
BAF57 is a core subunit present in all mammalian SWI/SNF ATP-dependent chromatin remodeling complexes, which regulates important biological processes including gene transcription, DNA recombination, DNA repair, and DNA replication. Among other functions, BAF57 mediates the recruitment of SWI/SNF...
Topics
- Adult
- Aged
- Aged, 80 and over
- Amino Acid Sequence
- Animals
- Breast Neoplasms
- COS Cells
- Cell Line, Transformed
- Cell Line, Tumor
- Chlorocebus aethiops
- Chromosomal Proteins, Non-Histone
- DNA-Binding Proteins
- Female
- Humans
- Middle Aged
- Molecular Sequence Data
- Mutation
- Neoplasm Staging