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Article

Orphaned ryanodine receptors in the failing heart.

Proceedings of the National Academy of Sciences of the United States of America - 14 Mar 2006

Song Long-Sheng, Sobie Eric A, McCulle Stacey, Lederer W J, Balke C William, Cheng Heping

Abstract excerpt

Heart muscle is characterized by a regular array of proteins and structures that form a repeating functional unit identified as the sarcomere. This regular structure enables tight coupling between electrical activity and Ca(2+) signaling. In heart failure, multiple cellular defects develop, inclu...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16537526
DOI: 10.1073/pnas.0509324103
PMCID: PMC1449688

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16537526-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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