Article
Interleukin 10.G microsatellite in the promoter region of the interleukin-10 gene in severe sepsis.
Chinese medical journal - 5 Feb 2006
Shu Qiang, Shi Chang-chun, Zhang Xiang-hong, Shi Zhuo, Shi Shan-shan, Fang Xiang-ming, Chen Qi-xing, Stuber Frank
Abstract excerpt
BACKGROUND: The highly polymorphic interleukin 10.G (IL10.G) microsatellite located in the promoter region of the interleukin-10 (IL-10) gene exerts a positive transcriptional regulatory effect on IL-10 gene expression and correlates with the in vitro IL-10 secretion. This study was conducted to investigate whether IL10.G microsatellite is associated with the incidence and/or the outcome of severe sepsis....
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