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Article

Effect of subinhibitory concentrations of antibiotics on mutation frequency in Streptococcus pneumoniae.

The Journal of antimicrobial chemotherapy - 1 May 2006

Henderson-Begg Stephanie K, Livermore David M, Hall Lucinda M C

Abstract excerpt

OBJECTIVES: To investigate the effect of subinhibitory concentrations of ciprofloxacin, streptomycin, trimethoprim, ampicillin and erythromycin on mutation frequency in Streptococcus pneumoniae. METHODS: Frequency of mutation to rifampicin resistance was determined in three clinical isolates grown with or without antibiotic treatment. dinB was analysed using PCR and DNA sequence determination. RESULTS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16531433
DOI: 10.1093/jac/dkl064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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