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Article

Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage.

The Journal of antimicrobial chemotherapy - 1 Oct 2003

Gustafsson Ingegerd, Sjölund Maria, Torell Erik, Johannesson Marie, Engstrand Lars, Cars Otto, Andersson Dan I

Abstract excerpt

BACKGROUND: We examined how prolonged antibiotic treatment affected the resistance and mutation frequency of human microflora isolated from intestine (Escherichia coli, enterococci spp.), pharynx (alpha-streptococci) and nostril (coagulase-negative staphylococci, CoNS). METHODS: Samples were collected from patients at the Center of Cystic Fibrosis (n=18) and the haematology ward (n=18) of the University Hospital,...

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Source

Identifiers

PMID: 12972454
DOI: 10.1093/jac/dkg427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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