Article
Biochemical characterization of the recombinant human Drosophila homologues Timekeeper and Andante involved in the Drosophila circadian oscillator.
Molecular and cellular biochemistry - 1 Jun 2005
Rasmussen Tine, Skjøth Iben H E, Jensen Hans H, Niefind Karsten, Boldyreff Brigitte, Issinger Olaf-Georg
Abstract excerpt
The Drosophila clock proteins timekeeper (CK2a(Tik)) and andante (CK2beta(And)) are mutated CK2alpha and CK2beta subunits, respectively. In order to revisit the hypothesis concerning a perturbation of the beta/beta and/or alpha/beta subunit association, involving the andante mutant we have cloned, expressed and purified the recombinant andante mutant CK2beta(And) and a CK2 holoenzyme composed of CK2beta(And) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
