Article
AM-3K, an anti-macrophage antibody, recognizes CD163, a molecule associated with an anti-inflammatory macrophage phenotype.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Jul 2006
Komohara Yoshihiro, Hirahara Junko, Horikawa Tomohiro, Kawamura Kyoko, Kiyota Emi, Sakashita Naomi, Araki Norie, Takeya Motohiro
Abstract excerpt
CD163 is a member of the scavenger receptor cysteine-rich superfamily restricted to the monocyte/macrophage lineage and is thought to be a useful marker for anti-inflammatory or alternatively activated macrophages. In this study we used mass spectrometric analysis to determine that the antigen recognized by the antibody AM-3K, which we previously generated as a tissue macrophage-specific monoclonal antibody, was...
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