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Article

The Scavenger Receptor CD163: Regulation, Promoter Structure and Genomic Organization

1 Jan 1999

Abstract excerpt

CD163 is a recently identified member of the scavenger receptor cysteine-rich superfamily expressed on peripheral blood monocytes and most tissue macrophages. We demonstrate that in vitro culture of human blood monocytes with recombinant M-CSF induces CD163 transcription. In contrast, dendritic differentiation in the presence of GM-CSF and IL-4 suppresses CD163 mRNA and protein levels. Because an important...

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PMID: 10725797
DOI: 10.1159/000028105

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