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Article

Modulation of dendritic cell trafficking to and from the airways.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2006

Jakubzick Claudia, Tacke Frank, Llodra Jaime, van Rooijen Nico, Randolph Gwendalyn J

Abstract excerpt

We investigated the fate of latex (LX) particles that were introduced into mice intranasally. Macrophages acquired the vast majority of particles and outnumbered LX particle-bearing airway dendritic cells (DCs) by at least two orders of magnitude. Yet alveolar macrophages were refractory to migration to the draining lymph node (DLN), and all transport to the DLN could be ascribed to the few LX(+) airway DCs. Upon...

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Source

Identifiers

PMID: 16517726
DOI: 10.4049/jimmunol.176.6.3578

Genes

CCR7
CCR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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