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Fibroblast growth factor signaling in embryonic and cancer stem cells

28 Feb 2006

Abstract excerpt

Cancer stem cells are cancer cells that originate from the transformation of normal stem cells. The most important property of any stem cell is the ability to self-renew. Through this property, there are striking parallels between normal stem cells and cancer stem cells. Both cell types share various markers of "stemness". In particular, normal stem cells and cancer stem cells utilize similar molecular mechanisms...

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PMID: 16516203
DOI: 10.1016/j.febslet.2006.01.095

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