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Roles of FGF signaling in stem cell self-renewal, senescence and aging

9 Oct 2011

Abstract excerpt

The aging process decreases tissue function and regenerative capacity, which has been associated with cellular senescence and a decline in adult or somatic stem cell numbers and self-renewal within multiple tissues. The potential therapeutic application of stem cells to reduce the burden of aging and stimulate tissue regeneration after trauma is very promising. Much research is currently ongoing to identify the...

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PMID: 21990129
DOI: 10.18632/aging.100369

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