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Fibroblast growth factor 2 enhances BMSC stemness through ITGA2‐dependent PI3K/AKT pathway activation

26 Aug 2024

Abstract excerpt

Bone marrow-derived mesenchymal stem cells (BMSC) are promising cellular reservoirs for treating degenerative diseases, tissue injuries, and immune system disorders. However, the stemness of BMSCs tends to decrease during in vitro cultivation, thereby restricting their efficacy in clinical applications. Consequently, investigating strategies that bolster the preservation of BMSC stemness and maximize therapeutic...

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PMID: 39188080
DOI: 10.1002/jcp.31423

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