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Article

A Frequent Thrombomodulin Amino Acid Dimorphism Is not Associated with Thrombophilia

1 Jan 1991

Abstract excerpt

We report a C/T dimorphism in the thrombomodulin (TM) gene that predicts an Ala455----Val replacement in the sixth EGF-like domain of TM. This dimorphism has allelic frequencies of 82 (Ala) and 18% (Val) in a normal population. In a group of protein C deficient patients and in a group of subjects with unexplained thrombophilia the allelic frequencies were found to be the same as in the normal population. This...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1651567
DOI: 10.1055/s-0038-1648181

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