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Article

Thrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women.

Gynecologic and obstetric investigation - 1 Jan 2002

Borg Anthony J, Higgins John R, Brennecke Shaun P, Moses Eric K

Abstract excerpt

Thrombomodulin plays an important role in thromboresistance. A common mutation of the gene at amino acid 455 producing valine instead of alanine has been implicated as being a risk factor in myocardial infarction and chronic heart disease. However, its link with pre-eclampsia remains controversial. This report explores the Ala455Val point mutation in 280 women as a predictor of pre-eclampsia with the conclusion...

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Identifiers

PMID: 12297717
DOI: 10.1159/000064696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Thrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women.PMID 12297717Read ↗

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